Resource Type

Journal Article 80

Conference Videos 2

Year

2024 1

2023 3

2022 8

2021 7

2020 6

2019 3

2018 3

2017 6

2016 7

2015 5

2014 9

2013 1

2012 1

2011 1

2010 9

2009 9

2003 1

2000 1

open ︾

Keywords

hepatitis B virus 6

COVID-19 4

Zika virus 3

antiviral 3

epidemiology 3

human immunodeficiency virus (HIV) 3

China 2

Ebola virus 2

Epstein-Barr virus 2

H7N9 2

SARS-CoV-2 2

Virus 2

adeno-associated virus 2

cervical cancer 2

cervical intraepithelial neoplasia 2

hemagglutinin 2

hepatocellular carcinoma 2

nasopharyngeal carcinoma 2

viral load 2

open ︾

Search scope:

排序： Display mode:

Importance of Viral Disease in Dairy Cow Fertility Review

D. Claire Wathes, Chike F. Oguejiofor, Carole Thomas, Zhangrui Cheng

Engineering 2020, Volume 6, Issue 1,   Pages 26-33 doi: 10.1016/j.eng.2019.07.020

Abstract:

Many viral diseases are endemic in cattle populations worldwide.There is also significant evidence that viral infections have additional actions in dairy cows, whichAcute infection with non-cytopathic bovine viral diarrhea virus (BVDV) in mid-gestation increases abortionBovine herpesvirus (BHV)-1 is most common in pre-pubertal heifers, and can slow their growth, delay breedingBoth Schmallenberg virus (SBV) and bluetongue virus (BTV) are transmitted by insect vectors and lead

Keywords： Bovine viral diarrhea virus     Bovine herpesvirus-1     Bovine herpesvirus-4     Schmallenberg virus     Bluetonguevirus     Immunosuppression     Embryo mortality    

HTML PDF Collect

Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging

Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 449-461 doi: 10.1007/s11684-017-0589-5

Abstract: In this review, we summarize and discuss the latest progress in the development of small-molecule viralsevere acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus, Ebola virus, and Zika virus.virus and host cells, disrupting viral endocytosis, disturbing membrane fusion, and interrupting viralWe also discuss some general strategies for developing small-molecule viral inhibitors.

Keywords： emerging and re-emerging viruses     small-molecule inhibitor     coronavirus     Ebola virus     Zika virus     life cycle    

HTML PDF Collect

Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas

Lan Yu, Xun Tian, Chun Gao, Ping Wu, Liming Wang, Bei Feng, Xiaomin Li, Hui Wang, Ding Ma, Zheng Hu

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 497-508 doi: 10.1007/s11684-017-0572-1

Abstract:

Viral infections cause at least 10%–15% of all human carcinomas.Over the last century, the elucidation of viral oncogenic roles in many cancer types has provided fundamentalknowledge on carcinogenetic mechanisms and established a basis for the early intervention of virus-relatedMeanwhile, rapidly evolving genome-editing techniques targeting viral DNA/RNA have emerged as novel therapeuticstrategies for treating virus-related carcinogenesis and have begun showing promising results.

Keywords： genome-editing tools     tumorigenic virus     delivery method     off-target effect     virus-related carcinoma    

HTML PDF Collect

Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy

Maliwan NACONSIE,Peng ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4,   Pages 285-294 doi: 10.15302/J-FASE-2016119

Abstract: Also, two viral diseases, cassava mosaic disease (CMD) and cassava brown streak disease (CBSD), causeGenetic engineering provides promising approaches to improve nutritional value and increase resistance to viralprotein content by overexpression of nutritious storage proteins and improving cassava resistance to viral

Keywords： Manihot esculenta     protein enhancement     RNA interference     transgenesis     virus resistance    

HTML PDF Collect

A brief review of microRNA and its role in PRRSV infection and replication

Xuekun GUO,Wenhai FENG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 114-120 doi: 10.15302/J-FASE-2014022

Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV), a single-stranded RNA virus, mainly infectsshown to be capable of modulating PRRSV infection and replication by multiple ways such as targeting viralgenomic RNA, targeting viral receptor and inducing antiviral response.MicroRNAs are small RNAs and have emerged as important regulators of virus-host cell interactions.

Keywords： porcine reproductive and respiratory syndrome virus (PRRSV)     microRNA     antiviral     viral tropism    

HTML PDF Collect

The past, present and future of bovine pluripotent stem cells: a brief overview

Xiuchun TIAN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 3-7 doi: 10.15302/J-FASE-2018247

Abstract:

Although the pursuit of bovine embryonic stem cells started more than 26 years ago for the purposecircuitry across mammalian species may be the main objective for studying pluripotent stem cells in the bovine

Keywords： bovine     embryonic     induced     pluripotent stem cells    

HTML PDF Collect

The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

Enfu Chen, Fenjuan Wang, Huakun Lv, Yanjun Zhang, Hua Ding, Shelan Liu, Jian Cai, Li Xie, Xiaoping Xu, Chengliang Chai, Haiyan Mao, Jimin Sun, Junfen Lin, Zhao Yu, Lianhong Li, Zhiping Chen, Shichang Xia

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 333-344 doi: 10.1007/s11684-013-0275-1

Abstract:

This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang ProvinceThe patient initially complained of diarrhea and influenza-like symptoms on March 7 and 14 respectivelyThis H7N9 virus from Zhejiang is highly similar to isolates obtained from Shanghai, Jiangsu, Anhui, etcPerson-to-person transmission of the H7N9 virus was not detected among close contacts, but such transmission

Keywords： avian influenza A (H7N9) virus     epidemiology     contacts     person-to-person transmission    

HTML PDF Collect

Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 33-41 doi: 10.15302/J-FASE-2018228

Abstract:

Female infertility represents a major challenge for improving the production efficiency in the dairy industry. Historically, fertility has declined whereas milk yield has increased tremendously due to intensive genetic selection. evidence reveals about 60% pregnancy loss takes place during the first month following fertilization. Meanwhile, early embryo development is significant for somatic cell nuclear transfer in cattle as a large proportion of cloned embryos fail to develop beyond peri-implantation stage. Oocyte quality is of utmost importance for the early embryo to develop to term for both fertilized and cloned embryos. Epigenetic reprogramming is a key process occurring after fertilization and critical roles of epigenetic modifiers during preimplantation development are now clear. Incomplete epigenetic reprogramming is believed to be a major limitation to cloning efficiency. Treatment of cloned embryos with epigenetic modifying drugs (e.g., Trichostatin A) could greatly improve cloning efficiency in both mice and cattle. Recently, the rapid progress in high-throughput sequencing technologies has enabled detailed deciphering of the molecular mechanisms underlying these events. The robust efficiency of genomic editing tools also presents an alternative approach to the functional annotation of genes critical to early development.

Keywords： bovine cloning     embryo development     somatic cell nuclear transfer     X-inactive specific transcript    

HTML PDF Collect

Innate immune responses in RNA viral infection

Qian Xu, Yuting Tang, Gang Huang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 333-346 doi: 10.1007/s11684-020-0776-7

Abstract: Upon viral invasion, the innate immune system responds rapidly and plays a key role in activating theIn this review, the current understanding of innate immunity contributing to the restriction of RNA viralBesides the main role of immune cells in combating viral infection, the intercellular transfer of pathogenThis knowledge provides an enhanced understanding of the innate immune response to RNA viral infectionsin general and aids in the preparation for the existing and next emerging viral infections.

Keywords： innate immune     viral infection     intercellular signaling     metabolic changes     epigenetic changes    

HTML PDF Collect

Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 139-143 doi: 10.1007/s11684-019-0736-2

Abstract: The rationale for the antibiotic treatment of viral community-acquired pneumonia (CAP) in adults wasClinical data from 166 patients diagnosed with viral pneumonia across 14 hospitals in Beijing from NovemberA total of 163 (98.3%) patients with viral pneumonia were treated with antibiotics.A total of 39 of the 163 (23.9%) patients did not meet the guidelines for drug selection for viral CAPThe unreasonable use of antibacterial drugs for the treatment of viral CAP in adults is a serious concern

Keywords： adult     antibiotic     viral pneumonia    

HTML PDF Collect

Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 271-276 doi: 10.1007/s11684-009-0054-1

Abstract: The aim of this paper is to investigate the relationship between hepatitis B virus (HBV) DNA levels during

Keywords： hepatitis B     chronic     viral load     liver cirrhosis    

HTML PDF Collect

Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling

Xiaorong Meng, Shanshan Huo, Lei Wang, Xudong Wang, Yongtao Lv, Weiting Tang, Rui Miao, Danxi Huang

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 2, doi: 10.1007/s11783-017-0907-9

Abstract: The effects of PES membrane interfacial electrokinetic property on the bovine serum albumin (BSA) membrane

Keywords： Charged PES UF membrane     BSA     Electrokinetic characterization     Adhesion force     Jump distance    

HTML PDF Collect

Removal of virus aerosols by the combination of filtration and UV-C irradiation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1627-y

Abstract:

● The removal of virus aerosols by filtration and UV-C irradiation

Keywords： Filtration system     UV-C irradiation     Virus aerosol     Public health     COVID-19    

HTML PDF Collect

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 260-267 doi: 10.15302/J-FASE-2016116

Abstract: The innate immune response is the first line of defense against viral invasion and pro-inflammatory chemokinesand cytokines have a critical function in the innate immune responses against virus infections.The ability of a rabies virus (RABV) to induce the expression of chemokines and cytokines can lead toviral clearance from the central nervous system (CNS), whereas the ability to evade such expressionenhancement of blood brain barrier permeability and activation of various immune cells that are essential for viral

Keywords： antiviral     blood brain barrier     chemokines and cytokines     innate immunity     rabies virus    

HTML PDF Collect

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 480-489 doi: 10.1007/s11684-017-0594-8

Abstract:

Superinfection is frequently detected among individuals infected by human immunodeficiency virus type

Keywords： human immunodeficiency virus type I     superinfection     incidence     immune response    

HTML PDF Collect

Title Author Date Type Operation

Importance of Viral Disease in Dairy Cow Fertility

D. Claire Wathes, Chike F. Oguejiofor, Carole Thomas, Zhangrui Cheng

Journal Article

Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging

Xiaohuan Wang, Peng Zou, Fan Wu, Lu Lu, Shibo Jiang

Journal Article

Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas

Lan Yu, Xun Tian, Chun Gao, Ping Wu, Liming Wang, Bei Feng, Xiaomin Li, Hui Wang, Ding Ma, Zheng Hu

Journal Article

Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy

Maliwan NACONSIE,Peng ZHANG

Journal Article

A brief review of microRNA and its role in PRRSV infection and replication

Xuekun GUO,Wenhai FENG

Journal Article

The past, present and future of bovine pluripotent stem cells: a brief overview

Xiuchun TIAN

Journal Article

The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

Enfu Chen, Fenjuan Wang, Huakun Lv, Yanjun Zhang, Hua Ding, Shelan Liu, Jian Cai, Li Xie, Xiaoping Xu, Chengliang Chai, Haiyan Mao, Jimin Sun, Junfen Lin, Zhao Yu, Lianhong Li, Zhiping Chen, Shichang Xia

Journal Article

Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Journal Article

Innate immune responses in RNA viral infection

Qian Xu, Yuting Tang, Gang Huang

Journal Article

Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Journal Article

Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Journal Article

Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling

Xiaorong Meng, Shanshan Huo, Lei Wang, Xudong Wang, Yongtao Lv, Weiting Tang, Rui Miao, Danxi Huang

Journal Article

Removal of virus aerosols by the combination of filtration and UV-C irradiation

Journal Article

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Journal Article

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Journal Article